SEE THINGS DIFFERENTLY

* Based on a 2019 American Society of Cataract and Refractive Surgery survey of 36 surgeons from 9 countries who rated the usability and ergonomics of a Clareon^® Monarch^® IV prototype compared with the Monarch^® III Delivery System.

† Thread enhanced from Monarch^® III

‡ Based on in vitro examinations of glistenings, surface haze and SSNGs.

 

IMPORTANT PRODUCT INFORMATION: CLAREON^® FAMILY OF IOLSCAUTION: Federal law restricts these devices to sale by or on the order of a physician.INDICATION: The family of Clareon^® intraocular lenses (IOLs) includes the Clareon^® Aspheric Hydrophobic Acrylic and Clareon^® Aspheric Toric IOLs, the Clareon^® PanOptix^® Trifocal Hydrophobic IOL, Clareon^® PanOptix^® Toric, Clareon^® Vivity^® Extended Vision Hydrophobic Posterior Chamber IOL and Clareon^® Vivity^® Toric IOLs. Each of these IOLs is indicated for visual correction of aphakia in adult patients following cataract surgery. In addition, the Clareon^® Toric IOLs are indicated to correct pre-existing corneal astigmatism at the time of cataract surgery. The Clareon^® PanOptix^® lens mitigates the effects of presbyopia by providing improved intermediate and near visual acuity, while maintaining comparable distance visual acuity with a reduced need for eyeglasses, compared to a monofocal IOL. The Clareon^® Vivity^® lens mitigates the effects of presbyopia by providing an extended depth of focus. Compared to an aspheric monofocal IOL, the lens provides improved intermediate and near visual acuity, while maintaining comparable distance visual acuity. All of these IOLs are intended for placement in the capsular bag.

WARNINGS/PRECAUTIONS: General cautions for all Clareon^® IOLs: Careful preoperative evaluation and sound clinical judgment should be used by the surgeon to decide the risk/benefit ratio before implanting any IOL in a patient with any of the conditions described in the Directions for Use that accompany each IOL. Physicians should target emmetropia, and ensure that IOL centration is achieved.

 

For the Clareon^® Aspheric Toric, PanOptix^® Toric and Vivity^® Toric IOLs, the lens should not be implanted if the posterior capsule is ruptured, if the zonules are damaged, or if a primary posterior capsulotomy is planned. Rotation can reduce astigmatic correction; if necessary lens repositioning should occur as early as possible prior to lens encapsulation.

 

For the Clareon^® PanOptix^® IOL, some visual effects may be expected due to the superposition of focused and unfocused multiple images. These may include some perceptions of halos or starbursts, as well as other visual symptoms. As with other multifocal IOLs, there is a possibility that visual symptoms may be significant enough that the patient will request explant of the multifocal IOL. A reduction in contrast sensitivity as compared to a monofocal IOL may be experienced by some patients and may be more prevalent in low lighting conditions. Therefore, patients implanted with multifocal IOLs should exercise caution when driving at night or in poor visibility conditions. Patients should be advised that unexpected outcomes could lead to continued spectacle dependence or the need for secondary surgical intervention (e.g., intraocular lens replacement or repositioning). As with other multifocal IOLs, patients may need glasses when reading small print or looking at small objects. Posterior capsule opacification (PCO), may significantly affect the vision of patients with multifocal IOLs sooner in its progression than patients with monofocal IOLs.

 

For the Clareon^® Vivity^® IOL, most patients implanted with the Vivity^® IOL are likely to experience significant loss of contrast sensitivity as compared to a monofocal IOL. Therefore, it is essential that prospective patients be fully informed of this risk before giving their consent for implantation of the Clareon^® Vivity^® IOL. In addition, patients should be warned that they will need to exercise caution when engaging in activities that require good vision in dimly lit environments, such as driving at night or in poor visibility conditions, especially in the presence of oncoming traffic. It is possible to experience very bothersome visual disturbances, significant enough that the patient could request explant of the IOL. In the parent AcrySof^® IQ Vivity^® IOL clinical study, 1% to 2% of AcrySof^® IQ Vivity^® IOL patients reported very bothersome starbursts, halos, blurred vision, or dark area visual disturbances; however, no explants were reported. Prior to surgery, physicians should provide prospective patients with a copy of the Patient Information Brochure available from Alcon informing them of possible risks and benefits associated with these IOLs.

ATTENTION: Reference the Directions for Use labeling for each IOL for a complete listing of indications, warnings and precautions.

IMPORTANT PRODUCT INFORMATION - CLAREON^®MONARCH^® IV IOL DELIVERY SYSTEM

CAUTION: Federal (USA) law restricts this device to sale by or on the order of a physician.

INDICATIONS: The CLAREON^® MONARCH^® IV IOL Delivery System is for implantation of qualified Alcon foldable IOLs. No unqualified lenses should be used with the CLAREON^® MONARCH^® IV IOL Delivery System.

WARNINGS: Consult the product labeling for the complications associated with the CLAREON^® MONARCH^® IV IOL Delivery System used in conjunction with cataract surgery and IOL implantation.

 

HANDPIECE PRECAUTIONS:

• A high level of surgical skill is required for intraocular lens implantation. The surgeon should have observed and/or assisted in numerous implantations and successfully completed one or more courses on intraocular lens implantation before attempting to implant intraocular lenses.
• Read all instructions prior to use.
• The handpiece is non-sterile and must be cleaned and sterilized prior to each use (refer to Handpiece Preparation section of this Instructions for Use).  Failure to properly sterilize handpiece could result in serious infection (e.g., endophthalmitis and systemic
• infection).
• Use of hydrogen peroxide may discolor titanium instruments.
• Mixing titanium and stainless-steel instruments during sterilization may result in discoloration of the instruments.
• If a patient with a prion-related disease undergoes a procedure which, in the medical opinion of the physician, poses a high risk of instrument contamination, the instrument should be destroyed or processed according to local requirements.

 

ATTENTION: Reference the Directions for Use labeling for a complete listing of indications and precautions.

 

REFERENCES:

1. Alcon Data on File, 2019.

2. Alcon Data on File, 2021.

3. Clareon^®Monarch^® IV IOL Delivery System - Proposed Instructions for use Final.

4. Werner L, Thatthamla I, Ong M, et al. Evaluation of clarity characteristics in a new hydrophobic acrylic IOL. J Cataract Refract Surg. 2019;45:1490-1497.

5. Lehmann, R., Maxwell, A., Lubeck, DM, Fong, R., Walters, TR, Fakadej, A. Effectiveness and Safety of the Clareon Monofocal Intraocular Lens: Outcomes    from a 12-Month Single-Arm Clinical Study in a Large Sample. Clin Ophthalmol. 2021;15:1647-1657. Published
2021 Apr 20.

6. Clareon^® PanOptix^® Trifocal Hydrophobic Acrylic IOL Model CNWTT0 Directions for Use.

7. Clareon^® Vivity^® Extended Vision Hydrophobic IOL (CNWET0) Directions for Use.

8. Alcon Data on File, 2020.

9. Lee B., Chang D. Comparison of the rotational stability of two toric intraocular lenses in 1273 consecutive eyes. Ophthalmology.2018;125(9):1325-1331.