Allows patients to wear contant lenses more comfortably1 and longer each day2
HydraGlyde® Moistue Matrix helps provide comfort from morning ‘til night.1-3
Dependable disinfection when tested in vitro in the presence of a lens.
In 2012, the FDA sponsored a series of studies to show the impact different lens materials have on the concentration and efficacy of disinfectant in tested multipurpose solutions.
Biocidal Efficacy of POLYQUAD®/ALDOX® Preservatives Against Staphylococcus aureus4†
Objectives: This study examined the interaction of seven different lens materials with a multipurpose solution (MPS) containing the disinfectants polyquaternium-1 (0.001%) and myristamoidopropyl dimethylamine (0.0005%). The objective of this study was to determine whether the different lens materials affect the concentration of a disinfectant against Staphylococcus aureus.
Methods: Silicone hydrogel lenses (galyfilcon A, senofilcon A, comfilcon A, enfilcon A, balafilcon A, and lotrafilcon B) and a conventional hydrogel lens (etafilcon A) were soaked in polypropylene lens cases filled with commercially available MPS containing 0.001% polyquaternium-1 and 0.0005% myristamidopropyl dimethylamine for 6, 12, 24, 72, and 168 hours. Empty lens cases containing the seven types of lenses and controls were assayed for activity against S. aureus according to International Standards Organization 14729 standard with modifications. Test solutions were analyzed for polyquaternium-1 and myristamidopropyl dimethylamine concentration at each time point.
Tested a polyquaternium-1 and myristamidopropyl solution against Staphylococcus aureus:
Biocidal Efficacy of PHMB Against Fusarium solani5†
Objectives: To investigate the effects of eight different soft contact lenses on disinfection efficacy of a multipurpose solution (MPS) containing poly-hexamethylene biguanide (PHMB, 0.0001%, 6-hour soak) against Fusarium solani.
Methods: Six silicone hydrogel lenses (galyfilcon A, senofilcon A, comfilcon A, enfilcon A, balafilcon A, and lotrifilcon B) and two conventional hydrogel lenses (polymacon and etafilcon A) were placed in polypropylene lens cases filled with MPS containing 0.0001% PHMB and soaked for 6, 12, 24, 72, and 168 hours. After each interval, depleted MPS from lens cases were removed and assayed for activity against F. solani according to International Organization for Standardization (ISO) 14729 stand-alone procedure. A portion was aliquoted for chemical analysis.
Tested a PHMB solution against Fusarium solani:
Biocidal Efficacy of PHMB Against Staphylococcus aureus6†
Objectives: To determine the effect of 8 different lens materials on polyhexamethylene biguanide (PHMB) concentration in a tested multipurpose solution (MPS, 0.0001% PHMB, 6-hour soak) over time and to determine the effect of lenses on lens solution microbial efficacy over time.
Methods: Silicone hydrogel lenses and conventional hydrogel lenses were soaked in polypropylene lens cases filled with contact lens MPS containing 1 ppm PHMB for 6, 12, 24, 72, and 168 hours. Cases filled with the same solution without lenses were controls. After each time period, solutions from cases with the 8 types of lenses and controls were assayed for activity against Staphylococcus aureus according to International Organization for Standardization-14729 with modifications. Solutions were analyzed for PHMB concentration at each time point.
Tested a PHMB solution against Staphylococcus aureus: