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Meet the Systane® Family - Designed for All Dry Eye Needs

 

Explore the Systane® family of products with specially designed formulations for all types of patients’ Dry Eye needs. Find the Systane® solution that is right for your patient, depending on their symptoms and underlying causes. Also, learn more about Systane® proprietary HP-Guar intelligent delivery system.

HP-Guar Technology

 

Hydroxypropyl-guar or HP-Guar acts as a gelling agent, creating an elastic matrix on the corneal surface upon installation, producing a protective environment and forming a bio-adhesive gel that binds specifically to the hydrophobic regions of the cornea, where integrity is compromised.1

 

Benefits of HP-Guar include:

  • Benefits of HP-Guar include:
  • Prolonged protection1,2
  • Greater hydration and lubrication compared to Hyaluronic Acid alone1,2*

*In vitro data

HP Guar image

Long-lasting relief4,6,7 of dry eyes caused by reduced tear production

 

Dry eyes with a lack of tear fluid indicate a secretion defect in the lacrimal gland. Basically, the lacrimal gland does not produce enough tear fluid.5

Systane Hydration PF packshot

For all types of dry eyes8

 

Some patients suffer from a combination of both evaporative dry eye, where the tears evaporate too quickly, and fluid deficiency dry eye, where the lacrimal gland does not produce enough tear fluid.5,9

Systane COMPLETE PF packshot

Fast-acting relief10,11 for dry eyes caused by lack of fluid

 

Dry eyes with a lack of tear fluid indicate a secretion defect in the lacrimal gland. Basically, the lacrimal gland does not produce enough tear fluid.5

Systane ULTRA PF packshot

References:
1. Based on internal calculations using third-party data; Alcon data on file, 2019
2. Clark L. Springs, Novel Hydroxypropyl-Guar Gellable Lubricant Eye Drops for Treatment of Dry Eye, Adv Ther (2010); 3. Labetoulle M, et al. Br J Ophthalmol 2017;101:487–492.
3. Mrukwa-Kominek E, Baranska K, Jadczyk K. First clinical reports on the application of the moderndualpolymer formula in aqueous deficiency dry eye syndrome: Polish observations. Presented at the20th ESCRS Winter Meeting; February 26-28, 2016, Athens, Greece.
4. Rangarajan R, Kraybill B, Ogundele A, Ketelson H. Effects of a Hyaluronic Acid/Hydroxypropyl Guar Artificial Tear Solution on Protection, Recovery, and Lubricity in Models of Corneal Epithelium. J. Ocul. Pharmacol. Ther. 2015;31(8):491-497.
5. Bron et al. TFOS DEWS II Pathophysiology Report The Ocular Surface 2017; 15(3): 438-510.
6. Davitt WF, Bloomenstein M, Christensen M, Martin AE. Efficacy in patients with dry eye after treatment with a new lubricant eye drop formulation. J Ocul Pharmacol Ther. 2010;26(4):347-353.
7. Rolando M, Autori S, Badino F, Barabino S. Protecting the ocular surface and improving the quality of life of dry eye patients: a study of the efficacy of an HP-guar containing ocular lubricant in a population of dry eye patients. J Ocul Pharmacol Ther. 2009;25(3):271-278.
8. Silverstein S. et al. Symptom Relief Following a Single Dose of Propylene Glycol-Hydroxypropyl Guar Nanoemulsion in Patients with Dry Eye Disease: A Phase IV, Multicenter Trial. Clinical Ophthalmology 2020:14 3167–3177
9. Lemp MA, Crews LA, Bron AJ, Foulks GN, Sullivan BD. Distribution of aqueous-deficient and evaporative dry eye in a clinic-based patient cohort: a retrospective study. Cornea. 2012;31:472–478.
10. Davitt WF, Bloomenstein M, Christensen M, Martin AE. Efficacy in patients with dry eye after treatment with a new lubricant eye drop formulation. J Ocul Pharmacol Ther. 2010 Aug;26(4):347-53. doi: 10.1089/jop.2010.0025. PMID: 20653478.
11. Christensen MT, Martin AE, Bloomenstein M. A comparison of efficacy between Systane Ultra and Optive lubricant eye drops when tested with dry eye patients. Optometry. 2009;80(6):315.

 

See instruction for use, precautions, warnings, contraindications and adverse effects.