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Trusted Science.
Proven Performance.
Affordable Price.

#1 SELLING PRESERVATIVE-FREE EYE DROP IN CANADA1

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product boxes for 10 mL bottles of Systane Hydration Preservative-Free lubricant eye drops and Systane Complete Preservative-Free lubricant eye drops by Alcon

Dry eye disease is on the rise due to a range of causes.2,3

 

Help your patients find real relief with SYSTANE® COMPLETE Preservative-Free.4

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Icon of people on a blue circle

Aging population

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Icon of a leaf on a blue circle

Pollution

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Smartphone icon on a blue circle

Digital device usage

Help your patients get dry eye relief

 

Give your patients instant and 12-hour relief with one drop of Systane® PRO Preservative-Free1*

 

*47% of patients experience meaningful symptom relief at 12 hours, N=153.

    SYSTANE® PRO PF

    Systane® PRO: For Up to 12 Hours of Dry Eye Relief1

     

    The ONLY triple-action, preservative-free formula that provides up to 12 hours of dry eye relief1*

    Hydrates, restores, and protects1

    Designed to treat all types of dry eye—aqueous, evaporative, and mixed1

    Contact lens friendly—safe for use with soft contact lenses†

    LEARN MORE

     

    * 47% of patients experience meaningful symptom relief at 12 hours, N=153.

    † Not a rewetting solution.

    SYSTANE® COMPLETE PF

    SYSTANE® COMPLETE:
For Instant and 8-hour Relief4

     

     Technology that restores and protects all 
layers of the tear film5*

    Replenishes the aqueous layer

    Acts on the lipid layer to increase thickness and prolong retention

    Stabilizes the tear film to prevent evaporation

    LEARN MORE

     

    * In vitro data.

    SYSTANE® HYDRATION PF

    SYSTANE® HYDRATION:
For Long-Lasting Relief

     

    Dual-polymer formula acts as a “bandage” to allow healing of damaged cells on the ocular surface7,8*

    For patients with sensitive eyes; LASIK or cataract patients seeking dry eye relief

    Preservative-Free

    Suitable for use with soft contact lenses9

    Improves eye comfort and quality of life in digital device users6†

    LEARN MORE

     

    * In vitro data.

    † End-of-the-day comfort: Visual analog scale score changes from 56.9 ± 21.5 (day 1) vs 74.9 ± 19.3 (wk 2). Based on a survey on impact of dry eye on daily life from baseline vs week 2. N=30. p<0.0001 for all. Dosing: Participants, on average, applied their drops 4.4 ± 0.8, 5.0 ± 1.5, and 5.1 ± 1.4 times per day on the first day, at 1 week, and at 2 weeks, respectively.

    Systane® PRO, COMPLETE, and HYDRATION

    provide effective dry eye relief for your patients

    Why SYSTANE®?

     

    As the #1 eye care professional recommended brand for dry eye in Canada,1 SYSTANE® offers a range of formulas that provides real, 
long-lasting relief for dry eye symptoms.4,7

    VIEW FULL SYSTANE® PORTFOLIO
    Side-by-side packaging of Systane Complete Preservative-Free and Systane Hydration Preservative-Free lubricant eye drops, 10 mL bottles.

    Explore the SYSTANE® portfolio

    Close-up of eye and eye drops
    Close-up of eye and eye drops

     

    Dry Eye Drops

     

    VIEW
    Close-up of eye and eye drops
    Close-up of eye and eye drops

     

    Preservative-Free

     

    VIEW
    Close-up of eye and eye drops
    Close-up of eye and eye drops

     

    Gels and Ointments

     

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    Close-up of eye and tablet
    Close-up of eye and tablet

     

    Eye Care

     

    VIEW

    References:

    1. Alcon data on file, 2025.

    2. MarketScope LLC. 2020 Dry Eye Products Report: A Global Market Analysis for 2019 to 2025. St. Louis, MO: MarketScope LLC; 2020.

    3. Farrand KF, Fridman M, Stillman IÖ, Schaumberg DA. Prevalence of diagnosed dry eye disease in the United States among adults aged 18 years and older. Am J Ophthalmol. 2017;182:90-98.

    4. Silverstein S, Yeu E, Tauber J, et al. Symptom relief following a single dose of propylene glycol-hydroxypropyl guar nanoemulsion in patients with dry eye disease: a phase IV, multicenter trial. Clin Ophthalmol. 2020;14:3167-3177.

    5. Rangarajan R, Ketelson H. Preclinical evaluation of a new hydroxypropyl-guar phospholipid nanoemulsion-based artificial tear formulation in models of corneal epithelium.  J Ocul Pharmacol Ther. 2019;35(1):32-37. 

    6. Pucker AD, Lievens C, McGwin G Jr, et al. Quality of life in digital device users who are treated with Systane Hydration PF. Clin Optom 2023;15:45-54.

    7. Rangarajan R, Kraybill B, Ogundele A, Ketelson H. Effects of a hyaluronic acid/hydroxypropyl guar artificial tear solution on protection, recovery, and lubricity in models of corneal epithelium. J Ocul Pharmacol Ther. 2015;31(8):491-497.

    8. Christensen MT, Cohen S, Rinehart J, et al. Akers F, Pemberton B, Bloomenstein M, Lesher M, Kaplan D, Meadows D, Meuse P, Hearn C, Stein JM. Clinical evaluation of an HP-guar gellable lubricant eye drop for the relief of dryness of the eye. Curr Eye Res. 2004;28(1):55-62.

    9. Alcon data on file, 2015.

     

     

     

     

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