SYSTANE® Products for Healthy Vision and Dry Eye Relief
There’s a SYSTANE® product that’s right for your patients, whether they need relief from dry eye symptoms or support for healthy vision.
Eye Drops for Dry Eye
SYSTANE® PRO Preservative-Free Lubricant Eye Drops
The ONLY triple-action, preservative-free formula that hydrates, restores, and protects all types of dry eye and relieves dry eyes for up to 12 hours.1*
Safe for use with soft contact lenses.†
SYSTANE® COMPLETE and SYSTANE® COMPLETE Preservative-Free Lubricant Eye Drops
Clinically proven to deliver instant and all day‡ dry eye relief for all types of dry eye. Special nano-lipid formula fills gaps in the lipid layer and prevents tear film evaporation. Available in a preservative-free formula.2-4
Safe for use with soft contact lenses.†
SYSTANE® HYDRATION and SYSTANE® HYDRATION Preservative-Free Lubricant Eye Drops
Features a dual polymer formula that creates an elastic "bandage" over the surface of the eye to support corneal healing and retains moisture 2X better than HA alone.§ For aqueous dry eye and post-operative patients.5,6
Safe for use with soft contact lenses.†
SYSTANE® ULTRA and SYSTANE® ULTRA Preservative-Free Lubricant Eye Drops
Clinically proven to deliver extended protection for high-performance dry eye symptom relief that lasts – available in a preservative-free formula.7,8
Safe for use with soft contact lenses.†
SYSTANE® BALANCE Lubricant Eye Drops
Helps support and restore the eyes’ delicate lipid layer.9
SYSTANE® Lubricant Eye Drops
Dry eye relief with the original formula, from SYSTANE®, the #1 doctor recommended brand for dry eyes in Canada.10
SYSTANE® BION TEARS® Lubricant Eye Drops
Provides soothing relief from serious dry eye, including Dry Eye related to Sjögren’s Syndrome in a preservative-free formula.11
HA = hyaluronic acid.
* 47% of patients experience meaningful symptom relief at 12 hours, N=153.
† Not a rewetting solution.
‡ 8 hours.
§ Based on an in vitro study.
Gels & Ointments for Dry Eye
SYSTANE® Gel Drops
Provides lasting relief from dry eye irritation. They are a thicker eye drop formulation that creates a protective shield over eyes. For moderate-to-severe dry eye sufferers.10
SYSTANE® Eye Ointment
Features lanolin in a formula designed to keep eyes lubricated and comfortable during sleep, for moderate-to-severe dry eye sufferers.
SYSTANE® Day & Night Eye Drops
Packs include SYSTANE® COMPLETE for comfort during the day, and SYSTANE® Gel Drops for extra protection at night.
Omega-3 & Lid Wipes
SYSTANE® Omega‑3 Supplement
Helps relieve symptoms of Dry Eye Syndrome. Helps support proper tear function, cognitive and cardiovascular health and brain function.
SYSTANE® Lid Wipes
Premium, pre-moistened eyelid cleansing wipes that can be used as part of a daily hygiene regimen.
All SYSTANE® Products
SYSTANE® PRO Preservative-Free Lubricant Eye Drops
The ONLY triple-action, preservative-free formula that hydrates, restores, and protects all types of dry eye and relieves dry eyes for up to 12 hours.1*
Safe for use with soft contact lenses.†
SYSTANE® COMPLETE and SYSTANE® COMPLETE Preservative-Free Lubricant Eye Drops
Clinically proven to deliver instant and all day‡ dry eye relief for all types of dry eye. Special nano-lipid formula fills gaps in the lipid layer and prevents tear film evaporation. Available in a preservative-free formula.2-4
Safe for use with soft contact lenses.†
SYSTANE® HYDRATION and SYSTANE® HYDRATION Preservative-Free Lubricant Eye Drops
Features a dual polymer formula that creates an elastic "bandage" over the surface of the eye to support corneal healing and retains moisture 2X better than HA alone.§ For aqueous dry eye and post-operative patients.5,6
Safe for use with soft contact lenses.†
SYSTANE® ULTRA and SYSTANE® ULTRA Preservative-Free Lubricant Eye Drops
Clinically proven to deliver extended protection for high-performance dry eye symptom relief that lasts – available in a preservative-free formula.7,8
Safe for use with soft contact lenses.†
SYSTANE® BALANCE Lubricant Eye Drops
Helps support and restore the eyes’ delicate lipid layer.9
SYSTANE® Lubricant Eye Drops
Dry eye relief with the original formula, from SYSTANE®, the #1 doctor recommended brand for dry eyes in Canada.10
SYSTANE® BION TEARS® Lubricant Eye Drops
Provides soothing relief from serious dry eye, including Dry Eye related to Sjögren’s Syndrome in a preservative-free formula.11
SYSTANE® Gel Drops
Provides lasting relief from dry eye irritation. They are a thicker eye drop formulation that creates a protective shield over eyes. For moderate-to-severe dry eye sufferers.10
SYSTANE® Eye Ointment
Features lanolin in a formula designed to keep eyes lubricated and comfortable during sleep, for moderate-to-severe dry eye sufferers.
SYSTANE® Day & Night Eye Drops
Packs include SYSTANE® COMPLETE for comfort during the day, and SYSTANE® Gel Drops for extra protection at night.
SYSTANE® Omega‑3 Supplement
Helps relieve symptoms of Dry Eye Syndrome. Helps support proper tear function, cognitive and cardiovascular health and brain function.
SYSTANE® Lid Wipes
Premium, pre-moistened eyelid cleansing wipes that can be used as part of a daily hygiene regimen.
*8 hours.
†Based on an in vitro study.
Important safety information
TO BE SURE THIS PRODUCT IS RIGHT FOR YOUR PATIENTS, ALWAYS READ AND FOLLOW THE LABEL.
References
1. Alcon data on file, 2025.
2. Silverstein S, Yeu E, Tauber J, et al. Symptom Relief Following a Single Dose of Propylene Glycol-Hydroxypropyl Guar Nanoemulsion in Patients with Dry Eye Disease: A Phase IV, Multicenter Trial. Clin Ophthalmol. 2020;14:3167-3177.
3. Yeu E, et al. Efficacy and Safety of Phospholipid Nanoemulsion-Based Ocular Lubricant for the Management of Various Subtypes of Dry Eye Disease: A Phase IV, Multicenter Trial. Clin Ophthalmol. 2020;14:2561-2570.
4. Ketelson H, Rangarajan R. Pre-clinical evaluation of a novel phospholipid nanoemulsion based lubricant eye drops. Poster presented at ARVO 2017, Baltimore, MD.
5. Rangarajan R, Kraybill B, Ogundele A, Ketelson H. Effects of a Hyaluronic Acid/Hydroxypropyl Guar Artificial Tear Solution on Protection, Recovery, and Lubricity in Models of Corneal Epithelium. J. Ocul Pharmacol Ther. 2015;31(8):491-497.
6. Carlson E, et al. Impact of Hyaluronic Acid-Containing Artificial Tear Products on Reepithelialization in an In Vivo Corneal Wound Model. J Ocul Pharmacol Ther. 2018;34(4):360-364.
7. Rolando M, Autori S, Badino F, Barabino S. Protecting the ocular surface and improving the quality of life of dry eye patients: a study of the efficacy of an HP-guar containing ocular lubricant in a population of dry eye patients. J Ocul Pharmacol Ther. 2009;25(3):271-278.
8. Christensen MT, Martin AE, Bloomenstein M. A comparison of efficacy between Systane Ultra and Optive lubricant eye drops when tested with dry eye patients. Optometry. 2009;80(6):315.
9. Benelli U. Systane lubricant eye drops in the management of ocular dryness. Clin Ophthalmol. 2011:5;783-790.
10. IQVIA - Share of Recommendations - Systane in Canada - Q1 2025 to Q4 2025.
11. Christensen M, Martin A, Meadows D. An evaluation of the efficacy and patient acceptance of a new lubricant eye gel. The American Academy of Optometry Annual Meeting; 2011; E-Abstract 115013.
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