Systane® HYDRATION PRESERVATIVE-FREE
Key Benefits
Systane® HYDRATION PRESERVATIVE-FREE Lubricant Eye Drops provide LONG-LASTING1-3 Dry Eye relief:
- Dual-action hydration of the ocular surface1 recommended for pre and post surgery dry eye symptoms relief5
- Supports the corneal healing process4
- Contains hyaluronic acid for 2x more moisture retention#
- Designed for moderate to severe Dry Eye sufferers*
- Suitable for use with soft contact lenses

#than hyaluronic acid alone in a laboratory study
*recommendation based on expected on eye viscosity
Features & Technology
- Combines HP-Guar and hyaluronic acid, shown to provide 2x greater moisture retention compared to drops which contain hyaluronic acid alone1^
- HP-Guar acts as an elastic matrix that holds the active ingredients (PEG/PG) on the ocular surface for rapid relief1-3
- Patented PureFlow® Technology ensures no contaminated liquid or air can be reintroduced into the container, enabling a preservative-free formulation6

Patient Benefits
- Ideal for long-lasting relief1-3 for tired, irritated Dry Eye
- Also recommended for LASIK or cataract patients seeking relief from Dry Eye symptoms5
- Suitable for moderate to severe Dry Eye sufferers*
- Can be used with soft contact lenses**
- 3 months expiry after opening
- Also available in convenient unit dose vials

*recommendation based on expected on-eye viscosity
**please refer to instructions for use
^in a laboratory study
References:
1. Rangarajan R, Kraybill B, Ogundele A, Ketelson H. Effects of a Hyaluronic Acid/Hydroxypropyl Guar Artificial Tear Solution on Protection, Recovery, and Lubricity in Models of Corneal Epithelium. J. Ocul. Pharmacol. Ther. 2015;31(8):491-497.
2. Davitt, WF, Bloomenstein M, Christensen M, Martin AE. Efficacy in patients with dry eye after treatment with a new lubricant eye drop formulation. J Ocul Pharmacol Ther. 2010;26(4):347-353.
3. Rolando M, Autori S, Badino F, Barabino S. Protecting the ocular surface and improving the quality of life of dry eye patients: a study of the efficacy of an HP-guar containing ocular lubricant in a population of dry eye patients. J Ocul Pharmacol Ther. 2009;25(3):271-278.
4. Carlson E, et al. Impact of Hyaluronic Acid-Containing Artificial Tear Products on Reepitheliazation in an In Vivo Corneal Wound Model. J Ocul Pharmacol Ther. 2018;34(4):360-364.
5. Favuzza et al. Clin Ophthalmol 2020; 14: 1769-1775.
6. McAnally CL, et al. Microbial Ingress Risk Evaluation of Novelia Multi-Dose Package for PG/HPG Nano-Emulsion Lubricant Eye Drops. Invest. Ophthalmol. Vis. Sci. 2022;63(7):1997 – A0327.
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