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Long-Lasting relief¹ for Aqueous Deficient Dry Eye

Key Benefits

Systane® HYDRATION Preservative Free is a LONG-LASTING¹ formula designed for Aqueous Deficient Dry Eye:

  • Dual-action hydration of the ocular surface¹.
  • Supports the corneal healing process1 2 †.
  • Advanced Preservative Free formula*.


Systane HYDRATION PF pack shot

Features & Technology

  • Combines HP-Guar® and hyaluronic acid, shown to provide 2x greater moisture retention compared to drops which contain hyaluronic acid alone¹.
  • HP-Guar® acts as an elastic matrix that holds the active ingredients polyethylene glycol (PEG/PG) on the ocular surface for rapid relief.
  • Patented PureFlow®Technology ensures no contaminated liquid or air can be reintroduced in the container enabling a preservative free formulation.


Features and Technology

Patient Benefits


  • Ideal for long-lasting relief for tired, irritated Dry Eye¹.
  • Also suitable for LASIK or cataract patients seeking relief from Dry Eye symptoms.
  • Suitable for moderate, chronic sufferers**.
  • Can be used while wearing contact lenses***.




mother and daughter on couch

†Artificial tears can help support corneal healing process after eye surgery.
*Also available in a preserved version
**Based on internal assessment and patient segmentation
***Please refer to instructions for use


  1. Alcon Data on file: Systane Hydration Preservative Free, 2021.
  2. Sanchez, M.A., Arriola-Villalobos, P., Torralbo-Jimenez, P., Girón, N., De la Heras, B., Vanrell, R.H., Alvarez-Barrientos, A. and Benítez-del-Castillo, J.M., 2010. The effect of preservative-free HP-Guar on dry eye after phacoemulsification: a flow cytometric study. Eye, 24(8), pp.1331-1337.