Cataract Extraction and Corneal Endothelial Protection
Certain clinical situations place undue stress on the corneal endothelium, retina, and other ocular structures. BSS PLUS® Irrigating Solution combines an energy source, a buffer, and an antioxidant to maximally protect and nourish the health of intraocular tissues.
The positive outcomes experienced in routine cataract surgery are the result of many improvements occurring over the last 30 years. Advanced phacoemulsification techniques and equipment, advanced intraocular lenses, advanced ophthalmic viscosurgical devices, and advanced drugs and solutions have all played important roles. BSS PLUS® Irrigating Solution has a key role in corneal endothelial protection during routine cataract procedures.
After intraocular surgery, corneal endothelial cellular morphologic changes are noted that are indicative of a stressed endothelial monolayer, which may be more susceptible to additional surgical trauma.
After 15 minutes of irrigation with BSS PLUS® Irrigating Solution, cellular-density was unchanged from preoperative values compared with balanced salt solution. BSS PLUS® Irrigating Solution was associated with less corneal swelling and a significantly higher percentage of hexagonal cells at two and seven days after surgery.1
Conclusion: BSS PLUS® Irrigating Solution protects the corneal endothelium by minimizing polymegathism and pleomorphism during short and long term irrigation of the anterior chamber, whereas balanced salt solution does not. 1
Corneal and Retinal Edema See More
The glutathione in BSS PLUS® Irrigating Solution is taken up by corneal endothelial cells2 and helps protect them from free radicals produced by the surgical incision, the microscope light and the phacoemulsification probe. Additionally, BSS PLUS® Irrigating Solution provides intraocular tissues with dextrose bicarbonate for an energy source and bicarbonate a natural buffer. Together they promote normal corneal thickness and enhance the endothelial pump function.
Surgically-induced corneal or retinal edema may be caused by:
- Low corneal endothelial cell counts
- Mechanical trauma from instruments used in phacoemulsification and vitrectomy
- Toxic effect on the tissues from:
- light sources
- oxygen-free radicals
Working with Viscoelastics See More
A study from Emory University explored the permeability of the viscoelastic layer and measured the flux of dextrose, a constituent of BSS PLUS® Irrigating Solution, across a layer of viscoelastic material over time.
Conclusion: ProVisc® and VISCOAT® Ophthalmic Viscosurgical Devices readily permit the diffusion of dextrose3; therefore, BSS PLUS® Irrigating Solution can continue to provide physiologic support to the corneal endothelium, even when viscoelastics are used.
Used in conjunction with viscoelastics, BSS PLUS® Irrigating Solution provides nourishment, promotes a safe environment, and helps restore health to ocular tissues. In fact, BSS PLUS® Irrigating Solution helps you successfully deal with routine surgical cases as well as difficult ones.