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See the Innovation for Yourself

Take a closer look at the EX-PRESS® Glaucoma Filtration Device with live action videos and animations of the device’s engineering and implantation — including live surgeries narrated by surgeons who have embraced this innovative alternative to the trabeculectomy.

Featured doctors are paid consultants of Alcon Laboratories.

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Case Videos

Watch this video for a step-by-step demonstration of the implantation procedure.

This animation goes step by step through glaucoma filtration surgery with the EX-PRESS® Glaucoma Filtration Device.
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This animation breaks down the implantation procedure of the EX-PRESS® Glaucoma Filtration Device step by step. [1:25]

EX-PRESS® Glaucoma Filtration Device – Crandall

Dr. Alan Crandall performs glaucoma filtration surgery.
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Watch as Dr. Alan Crandall performs the EX-PRESS® Glaucoma Filtration Device implantation procedure. [12:15]

Watch as Dr. Ike Ahmed takes you step-by-step through a live EX-PRESS® Glaucoma Filtration Device implantation, offering pearls along the way.

Dr. Ike Ahmed walks you through the implantation procedure for the EX-PRESS® Glaucoma Filtration Device.
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Watch Dr. Ike Ahmed perform live surgery using the EX-PRESS® Glaucoma Filtration Device. [11:01]

Watch this animation to see how simple it can be to combine glaucoma filtration and cataract surgeries.

Cataract surgery and glaucoma filtration surgery in a single procedure.
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The order of the steps is a little different when you combine EX-PRESS® Glaucoma Filtration Device implantation with cataract surgery, but the procedures are similar. Watch this animation to see how it's done. [5:26]

Live EX-PRESS® Glaucoma Filtration Device/IOL Implantation

Dr. Garry Condon performs a combined cataract surgery and glaucoma filtration surgery.
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Watch Dr. Garry Condon combine glaucoma filtration and cataract surgeries. [10:42]
Product Videos

Trabeculectomy vs. EX-PRESS® Glaucoma Filtration Device

See for yourself which is more invasive: Trabeculectomy or EX-PRESS® Glaucoma Filtration Device implantation.
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Watch this video comparing the EX-PRESS® Glaucoma Filtration Device’s implantation procedure and a trabeculectomy side by side. [1:41]

See the innovative six-point engineering up close.

Get a close-up look at Lumenal Control and see the breakthrough in glaucoma filtration surgery for yourself.
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See the EX-PRESS® Glaucoma Filtration Device’s innovative six-point engineering up close. [0:57]

Take an up-close look at the pinpoint engineering of the EX-PRESS® Glaucoma Filtration Device.

See the precise specifications of the EX-PRESS® Glaucoma Filtration Device.
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Examine the six-point engineering of the EX-PRESS® Glaucoma Filtration Device and see which is bigger: the EX-PRESS® Glaucoma Filtration Device or a sesame seed. [0:42]
Guides and News

Procedural Guide

This illustrated, step-by-step procedural guide walks you through the EX-PRESS® Glaucoma Filtration Device implantation surgery.

2011 American Glaucoma Society Symposium

Read this Glaucoma Today supplement to find out why practitioners were praising the EX-PRESS® Glaucoma Filtration Device at the 2011 American Glaucoma Society Symposium. Also included are surgical pearls for EX-PRESS® Glaucoma Filtration Device implantation.

Glaucoma Today Supplement

This Glaucoma Today supplement includes more surgical pearls — and more praise — for the EX-PRESS® Glaucoma Filtration Device from surgeons throughout North America.

Ophthalmology Times Supplement

This Ophthalmology Times supplement features surgical pearls from a variety of practitioners who favor the uniformity and complication profile that the EX-PRESS® Glaucoma Filtration Device offers. Also included are patient selection tips and surgical pearls.

2011 World Glaucoma Congress

Find out how practitioners attending the 2011 World Glaucoma Congress determined that the statistical and empirical evidence favors the EX-PRESS® Glaucoma Filtration Device over surgical trabeculectomy.

2011 ASCRS-ASOA Symposium and Congress

Find out why surgeons gathered together to discuss the advantages of the EX-PRESS® Glaucoma Filtration Device at the 2011 ASCRS-ASOA Symposium and Congress in San Diego.

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See Important Product Information for:
EX-PRESS® Glaucoma Filtration Device +

EX-PRESS® Glaucoma Filtration Device

CAUTION: Federal (USA) law restricts this device to sale by, or on the order of, a physician.

INDICATION: The EX-PRESS® Glaucoma Filtration Device is intended to reduce intraocular pressure in glaucoma patients where medical and conventional surgical treatments have failed.

GUIDANCE REGARDING THE SELECTION OF THE APPROPRIATE VERSION: Prior clinical studies were not designed to compare between the various versions of the EX-PRESS® Glaucoma Filtration Device. The selection of the appropriate version is according to the doctor’s discretion.

CLINICAL STUDY INFORMATION: A clinical study was performed with the EX-PRESS® Glaucoma Filtration Device versions R-30 and R-50. The study was a prospective, open-label multi-center study of 113 open angle glaucoma patients with a follow-up period of one year. Results indicated an 80.4% overall success for the per-protocol cohort (R-30 and R-50, n=58) at one year, where overall success was defined as an IOP reduction greater than 20% from baseline with or without medications. Results indicated a 75.9% overall success for the per-protocol cohort (R-30 and R-50, n=58) at one year, where overall success was defined as an IOP of less than 21 mmHg with or without medications. The mean IOP reduction at one year was 33.8%. The percentage reduction from baseline was greater than 28% for the R-30 version and greater than 40% for the R-50 version.

The overall average number of glaucoma medications dropped significantly from 1.55 pre-operative to 0.52 medications at one-year postoperative.

The clinical study was not designed to compare between the various versions of the EX-PRESS® Glaucoma Filtration Device. The selection of the appropriate version is according to the doctor’s discretion. The most commonly reported adverse events included the need for further filtering surgery, device explantation, bleb revision and iris touch. Reasons for device explantation included flat anterior chamber with hypotony, device exposure from erosion, and poor efficacy. Other adverse events such as, but not limited to, corneal and retinal complications, uveitis, and significant reduction in visual acuity, may occur as well.

CONTRAINDICATIONS: The use of this device is contraindicated if one or more of the following conditions exist:

  • Presence of ocular disease such as uveitis, ocular infection, severe dry eye, severe blepharitis.
  • Pre-existing ocular or systemic pathology that, in the opinion of the surgeon, is likely to cause postoperative complications following implantation of the device.
  • Patients diagnosed with angle closure glaucoma.

WARNINGS/PRECAUTIONS: The use of this device is contraindicated if one or more of the following conditions exist:

  • The surgeon should be familiar with the directions for use.
  • The integrity of the package should be examined prior to use and the device should not be used if the package is damaged and sterility is compromised.
  • This device is for single use only.
  • MRI of the head is permitted, however not recommended, in the first two weeks post implantation.

ATTENTION: Reference the Directions for Use labeling for a complete listing of indications, warnings, precautions, complications and adverse events.

EX-PRESS® Glaucoma Filtration Device

CAUTION: Federal (USA) law restricts this device to sale by, or on the order of, a physician.

INDICATION: The EX-PRESS® Glaucoma Filtration Device is intended to reduce intraocular pressure in glaucoma patients where medical and conventional surgical treatments have failed.

GUIDANCE REGARDING THE SELECTION OF THE APPROPRIATE VERSION: Prior clinical studies were not designed to compare between the various versions of the EX-PRESS® Glaucoma Filtration Device. The selection of the appropriate version is according to the doctor’s discretion.

CLINICAL STUDY INFORMATION: A clinical study was performed with the EX-PRESS® Glaucoma Filtration Device versions R-30 and R-50. The study was a prospective, open-label multi-center study of 113 open angle glaucoma patients with a follow-up period of one year. Results indicated an 80.4% overall success for the per-protocol cohort (R-30 and R-50, n=58) at one year, where overall success was defined as an IOP reduction greater than 20% from baseline with or without medications. Results indicated a 75.9% overall success for the per-protocol cohort (R-30 and R-50, n=58) at one year, where overall success was defined as an IOP of less than 21 mmHg with or without medications. The mean IOP reduction at one year was 33.8%. The percentage reduction from baseline was greater than 28% for the R-30 version and greater than 40% for the R-50 version.

The overall average number of glaucoma medications dropped significantly from 1.55 pre-operative to 0.52 medications at one-year postoperative.

The clinical study was not designed to compare between the various versions of the EX-PRESS® Glaucoma Filtration Device. The selection of the appropriate version is according to the doctor’s discretion. The most commonly reported adverse events included the need for further filtering surgery, device explantation, bleb revision and iris touch. Reasons for device explantation included flat anterior chamber with hypotony, device exposure from erosion, and poor efficacy. Other adverse events such as, but not limited to, corneal and retinal complications, uveitis, and significant reduction in visual acuity, may occur as well.

CONTRAINDICATIONS: The use of this device is contraindicated if one or more of the following conditions exist:

  • Presence of ocular disease such as uveitis, ocular infection, severe dry eye, severe blepharitis.
  • Pre-existing ocular or systemic pathology that, in the opinion of the surgeon, is likely to cause postoperative complications following implantation of the device.
  • Patients diagnosed with angle closure glaucoma.

WARNINGS/PRECAUTIONS: The use of this device is contraindicated if one or more of the following conditions exist:

  • The surgeon should be familiar with the directions for use.
  • The integrity of the package should be examined prior to use and the device should not be used if the package is damaged and sterility is compromised.
  • This device is for single use only.
  • MRI of the head is permitted, however not recommended, in the first two weeks post implantation.

ATTENTION: Reference the Directions for Use labeling for a complete listing of indications, warnings, precautions, complications and adverse events.